Development and application of neural stem cells for treating various human neurological diseases in animal models
Identifieur interne : 000E09 ( Main/Exploration ); précédent : 000E08; suivant : 000E10Development and application of neural stem cells for treating various human neurological diseases in animal models
Auteurs : Bo-Rim Yi [Corée du Sud] ; Seung U. Kim [Canada, Corée du Sud] ; Kyung-Chul Choi [Corée du Sud]Source :
- Laboratory Animal Research [ 1738-6055 ] ; 2013.
Abstract
Stem cells derived from adult tissues or the inner cell mass (ICM) of embryos in the mammalian blastocyst (BL) stage are capable of self-renewal and have remarkable potential for undergoing lineage-specific differentiation under
Url:
DOI: 10.5625/lar.2013.29.3.131
PubMed: 24106507
PubMed Central: 3791346
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Development and application of neural stem cells for treating various human neurological diseases in animal models</title><author><name sortKey="Yi, Bo Rim" sort="Yi, Bo Rim" uniqKey="Yi B" first="Bo-Rim" last="Yi">Bo-Rim Yi</name><affiliation wicri:level="1"><nlm:aff id="A1">Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju</wicri:regionArea><wicri:noRegion>Cheongju</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Seung U" sort="Kim, Seung U" uniqKey="Kim S" first="Seung U." last="Kim">Seung U. Kim</name><affiliation wicri:level="1"><nlm:aff id="A2">Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Medical Research Institute, College of Medicine, Chung-Ang University, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Medical Research Institute, College of Medicine, Chung-Ang University, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Choi, Kyung Chul" sort="Choi, Kyung Chul" uniqKey="Choi K" first="Kyung-Chul" last="Choi">Kyung-Chul Choi</name><affiliation wicri:level="1"><nlm:aff id="A1">Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju</wicri:regionArea><wicri:noRegion>Cheongju</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24106507</idno><idno type="pmc">3791346</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791346</idno><idno type="RBID">PMC:3791346</idno><idno type="doi">10.5625/lar.2013.29.3.131</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000C56</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000C56</idno><idno type="wicri:Area/Pmc/Curation">000C56</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000C56</idno><idno type="wicri:Area/Pmc/Checkpoint">000678</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000678</idno><idno type="wicri:Area/Ncbi/Merge">001585</idno><idno type="wicri:Area/Ncbi/Curation">001585</idno><idno type="wicri:Area/Ncbi/Checkpoint">001585</idno><idno type="wicri:doubleKey">1738-6055:2013:Yi B:development:and:application</idno><idno type="wicri:Area/Main/Merge">000E21</idno><idno type="wicri:Area/Main/Curation">000E09</idno><idno type="wicri:Area/Main/Exploration">000E09</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Development and application of neural stem cells for treating various human neurological diseases in animal models</title><author><name sortKey="Yi, Bo Rim" sort="Yi, Bo Rim" uniqKey="Yi B" first="Bo-Rim" last="Yi">Bo-Rim Yi</name><affiliation wicri:level="1"><nlm:aff id="A1">Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju</wicri:regionArea><wicri:noRegion>Cheongju</wicri:noRegion></affiliation></author><author><name sortKey="Kim, Seung U" sort="Kim, Seung U" uniqKey="Kim S" first="Seung U." last="Kim">Seung U. Kim</name><affiliation wicri:level="1"><nlm:aff id="A2">Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>Division of Neurology, Department of Medicine, University of British Columbia, Vancouver, British Columbia</wicri:regionArea><wicri:noRegion>British Columbia</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Medical Research Institute, College of Medicine, Chung-Ang University, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Medical Research Institute, College of Medicine, Chung-Ang University, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Choi, Kyung Chul" sort="Choi, Kyung Chul" uniqKey="Choi K" first="Kyung-Chul" last="Choi">Kyung-Chul Choi</name><affiliation wicri:level="1"><nlm:aff id="A1">Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Laboratory of Veterinary Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju</wicri:regionArea><wicri:noRegion>Cheongju</wicri:noRegion></affiliation></author></analytic><series><title level="j">Laboratory Animal Research</title><idno type="ISSN">1738-6055</idno><idno type="eISSN">2233-7660</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Stem cells derived from adult tissues or the inner cell mass (ICM) of embryos in the mammalian blastocyst (BL) stage are capable of self-renewal and have remarkable potential for undergoing lineage-specific differentiation under <italic>in vitro</italic> culturing conditions. In particular, neural stem cells (NSCs) that self-renew and differentiate into major cell types of the brain exist in the developing and adult central nervous system (CNS). The exact function and distribution of NSCs has been assessed, and they represent an interesting population that includes astrocytes, oligodendrocytes, and neurons. Many researchers have demonstrated functional recovery in animal models of various neurological diseases such as stroke, Parkinson's disease (PD), brain tumors, and metastatic tumors. The safety and efficacy of stem cell-based therapies (SCTs) are also being evaluated in humans. The therapeutic efficacy of NSCs has been shown in the brain disorder-induced animal models, and animal models may be well established to perform the test before clinical stage. 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sortKey="Yi, Br" uniqKey="Yi B">BR Yi</name></author><author><name sortKey="Kim, Su" uniqKey="Kim S">SU Kim</name></author><author><name sortKey="Kim, Yb" uniqKey="Kim Y">YB Kim</name></author><author><name sortKey="Lee, Hj" uniqKey="Lee H">HJ Lee</name></author><author><name sortKey="Cho, Mh" uniqKey="Cho M">MH Cho</name></author><author><name sortKey="Choi, Kc" uniqKey="Choi K">KC Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, Y" uniqKey="Tang Y">Y Tang</name></author><author><name sortKey="Shah, K" uniqKey="Shah K">K Shah</name></author><author><name sortKey="Messerli, Sm" uniqKey="Messerli S">SM Messerli</name></author><author><name sortKey="Snyder, E" uniqKey="Snyder E">E Snyder</name></author><author><name sortKey="Breakefield, X" uniqKey="Breakefield X">X Breakefield</name></author><author><name sortKey="Weissleder, R" uniqKey="Weissleder R">R Weissleder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vermes, A" uniqKey="Vermes A">A Vermes</name></author><author><name sortKey="Guchelaar, Hj" uniqKey="Guchelaar H">HJ Guchelaar</name></author><author><name sortKey="Dankert, J" uniqKey="Dankert J">J Dankert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Okano, H" uniqKey="Okano H">H Okano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gage, Fh" uniqKey="Gage F">FH Gage</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Canada</li><li>Corée du Sud</li></country><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Yi, Bo Rim" sort="Yi, Bo Rim" uniqKey="Yi B" first="Bo-Rim" last="Yi">Bo-Rim Yi</name></noRegion><name sortKey="Choi, Kyung Chul" sort="Choi, Kyung Chul" uniqKey="Choi K" first="Kyung-Chul" last="Choi">Kyung-Chul Choi</name><name sortKey="Kim, Seung U" sort="Kim, Seung U" uniqKey="Kim S" first="Seung U." last="Kim">Seung U. Kim</name></country><country name="Canada"><noRegion><name sortKey="Kim, Seung U" sort="Kim, Seung U" uniqKey="Kim S" first="Seung U." last="Kim">Seung U. Kim</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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